Cosmetic Manufacturing: Glabridin Series

Introduction to Glabridin:

Glabridin is an exceptional whitening agent derived exclusively from the rare licorice species known as Glycyrrhiza glabra. With only 100 grams of Glabridin extracted from 1000 kilograms of licorice, its scarcity and extraction difficulty make it as valuable as physical gold. Through testing its ability to inhibit melanin production (IC50 value), Glabridin’s whitening effect has been found to be 232 times more potent than Vitamin C. Furthermore, Glabridin boasts anti-inflammatory and antioxidant properties, validated by FDA testing to ensure skin safety. Its premium skincare value and price tag have earned Glabridin the reputation of “whitening gold.” As a flavonoid, Glabridin is sourced from the precious botanical Glycyrrhiza glabra.

Functions of Glabridin in Cosmetics:

Whitening Effect: Glabridin inhibits tyrosinase activity and melanin synthesis, effectively whitening the skin. Tyrosinase is an essential enzyme involved in melanin production; inhibiting its activity suppresses melanin synthesis. Experimental evidence demonstrates Glabridin’s significant inhibition of tyrosinase, with its effect on melanin inhibition being hundreds of times more potent than other whitening agents, notably 232 times stronger than Vitamin C.
Antioxidant Effect: Glabridin exhibits antioxidant properties, reducing the formation of oxidized low-density lipoprotein (LDL) and preventing the attachment of oxidized lipid bodies to the inner walls of capillaries, thus maintaining capillary patency and preserving the normal vitality of peripheral skin cells.
Anti-inflammatory Effect: Glabridin reduces inflammation caused by factors such as UV radiation and chemical irritants, minimizing inflammation-induced cell death and preventing the collapse of skin’s inner layer cells caused by the toxicity of post-inflammatory cell death, thereby exerting anti-aging effects and reducing pigmentation caused by inflammation.
Antibacterial Effect: Glabridin is a whitening ingredient with excellent efficacy, comprehensive functions, and high safety. It eliminates free radicals and melanin in the skin, serving as a whitening and anti-aging miracle. Due to its low content, with only 100 grams extracted from 1000 kilograms of licorice, coupled with the cumbersome extraction and purification process, it is often dubbed the “whitening gold.” Mercury and hydroquinone mainly whiten the skin by killing melanocytes through cytotoxicity, which can cause harm to normal cells with prolonged use. Glabridin, on the other hand, is a whitening raw material without cytotoxicity.Widely used in internationally renowned brands such as Lancome, Dior, Sonia Rykiel, and Chanel.
Dosage and Formulation Integration:

In cosmetics, Glabridin is typically used at concentrations ranging from 0.001% to 3% to achieve whitening effects. For preventing skin darkening, line spots, and sunspots, the concentration can be reduced to 0.0007-0.05%. Additionally, for inhibiting male hormones and treating acne, the concentration of Glabridin ranges from 0.01% to 0.5%.

During production, purified and concentrated Glabridin extracts are incorporated into cosmetic formulations to maximize their skincare benefits.Dinghui Cosmetic OEM factory meticulously blend Glabridin with other ingredients to produce creams, serums, lotions, and masks, ensuring product stability, safety, and desired sensory properties for consumers.

Quality Control Measures:

Throughout the manufacturing process, stringent quality control measures are implemented to ensure the purity, efficacy, and safety of Glabridin-based cosmetic products. This includes rigorous testing of raw materials, process monitoring, and final product analysis to meet regulatory standards and industry guidelines.

As a Product Manager at Dinghui Cosmetics, we adhere to these principles to deliver high-quality cosmetic products to our consumers.